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Intracellular Proton-mediated Activation of TRPV3 Channels Accounts for the Exfoliation Effect of α-Hydroxyl Acids on Keratinocytes

α-Hydroxyl acids (AHAs) from natural sources act as proton donors and topical compounds that penetrate skin and are well known in the cosmetic industry for their use in chemical peels and improvement of the skin. However, little is known about how AHAs cause exfoliation to expose fresh skin cells. H...

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Autores principales: Cao, Xu, Yang, Fan, Zheng, Jie, Wang, KeWei
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406675/
https://ncbi.nlm.nih.gov/pubmed/22679014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.364869
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