Divalent cations potentiate TRPV1 channel by lowering the heat activation threshold

Transient receptor potential vanilloid type 1 (TRPV1) channel responds to a wide spectrum of physical and chemical stimuli. In doing so, it serves as a polymodal cellular sensor for temperature change and pain. Many chemicals are known to strongly potentiate TRPV1 activation, though how this is achi...

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Bibliographic Details
Main Authors: Cao, Xu, Ma, Linlin, Yang, Fan, Wang, KeWei, Zheng, Jie
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2014
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874569/
https://ncbi.nlm.nih.gov/pubmed/24344247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201311025
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