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Intracellular Proton-mediated Activation of TRPV3 Channels Accounts for the Exfoliation Effect of α-Hydroxyl Acids on Keratinocytes

α-Hydroxyl acids (AHAs) from natural sources act as proton donors and topical compounds that penetrate skin and are well known in the cosmetic industry for their use in chemical peels and improvement of the skin. However, little is known about how AHAs cause exfoliation to expose fresh skin cells. H...

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Detalhes bibliográficos
Main Authors: Cao, Xu, Yang, Fan, Zheng, Jie, Wang, KeWei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406675/
https://ncbi.nlm.nih.gov/pubmed/22679014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.364869
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