Tumor Necrosis Factor Receptor-associated Factor Family Protein 2 Is a Key Mediator of the Epidermal Growth Factor-induced Ribosomal S6 Kinase 2/cAMP-responsive Element-binding Protein/Fos Protein Signaling Pathway

TRAF2 has an important function in mediating the TNF-R signaling pathway toward activation of NF-κB and JNKs. Here we reveal a novel function of TRAF2 in the epidermal growth factor (EGF) signaling pathway. Knockdown of TRAF2 blocked EGF-induced AP-1 activity and anchorage- independent cell transfor...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Peng, Cong, Zhu, Feng, Wen, Weihong, Yao, Ke, Li, Shengqing, Zykova, Tatyana, Liu, Kangdong, Li, Xiang, Ma, Wei-Ya, Bode, Ann M., Dong, Zigang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406673/
https://ncbi.nlm.nih.gov/pubmed/22685297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.359521
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados