Trisomy chromosome 5 is a recurrent cytogenetic lesion in mammary tumors from parous MMTV-erbB-2 transgenic mice

erbB-2 is amplified or overexpressed in approximately 30% of human breast cancers, and has been associated with poor prognosis and therapeutic resistance. Previous studies have suggested that erbB-2 overexpression in transgenic mice induces genomic instability; however, the patterns of genetic lesio...

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Main Authors: KIM, YOUNG MI, MA, ZHIKUN, LEE, SEUNGJIK, LEE, JIYUN, LI, SHIBO, YANG, XIAOHE
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2011
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406573/
https://ncbi.nlm.nih.gov/pubmed/22848270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2011.373
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