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PI3K expression and PIK3CA mutations are related to colorectal cancer metastases

AIM: To assess the significance of phosphatidylinositol 3-kinase (PI3K) in colorectal cancer (CRC) and toxicity of LY294002 in CRC cells with different metastatic abilities. METHODS: Sixty formalin-fixed and paraffin-embedded CRC tumor specimens were investigated. Adjacent normal colonic mucosa spec...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Zhu, Yu-Fen, Yu, Bao-Hua, Li, Da-Li, Ke, Hong-Lin, Guo, Xian-Zhi, Xiao, Xiu-Ying
Format: Artigo
Langue:Inglês
Publié: Baishideng Publishing Group Co., Limited 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406429/
https://ncbi.nlm.nih.gov/pubmed/22851869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v18.i28.3745
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