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Long telomeres bypass the requirement for telomere maintenance in human tumorigenesis

Despite the importance of telomere maintenance in cancer cell survival via the elongation of telomeres by telomerase reverse transcriptase (TERT) or Alternative Lengthening of Telomeres (ALT), it had not been tested directly whether telomere maintenance is dispensable for human tumorigenesis. We eng...

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Détails bibliographiques
Auteurs principaux: Taboski, Michael A. S., Sealey, David C. F., Dorrens, Jennifer, Tayade, Chandrakant, Betts, Dean H., Harrington, Lea
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406325/
https://ncbi.nlm.nih.gov/pubmed/22832159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2011.12.004
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