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Telomere Maintenance and Survival in Saccharomyces cerevisiae in the Absence of Telomerase and RAD52
Telomeres are essential features of linear genomes that are crucial for chromosome stability. Telomeric DNA is usually replenished by telomerase. Deletion of genes encoding telomerase components leads to telomere attrition with each cycle of DNA replication, eventually causing cell senescence or dea...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Genetics Society of America
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2710150/ https://ncbi.nlm.nih.gov/pubmed/19380905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.109.102939 |
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