Telomere Maintenance and Survival in Saccharomyces cerevisiae in the Absence of Telomerase and RAD52

Telomeres are essential features of linear genomes that are crucial for chromosome stability. Telomeric DNA is usually replenished by telomerase. Deletion of genes encoding telomerase components leads to telomere attrition with each cycle of DNA replication, eventually causing cell senescence or dea...

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Bibliographic Details
Main Authors: LeBel, Catherine, Rosonina, Emanuel, Sealey, David C. F., Pryde, Fiona, Lydall, David, Maringele, Laura, Harrington, Lea A.
Format: Artigo
Language:Inglês
Published: Genetics Society of America 2009
Subjects:
Investigations
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2710150/
https://ncbi.nlm.nih.gov/pubmed/19380905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.109.102939
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