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Telomere Maintenance and Survival in Saccharomyces cerevisiae in the Absence of Telomerase and RAD52

Telomeres are essential features of linear genomes that are crucial for chromosome stability. Telomeric DNA is usually replenished by telomerase. Deletion of genes encoding telomerase components leads to telomere attrition with each cycle of DNA replication, eventually causing cell senescence or dea...

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Bibliografiske detaljer
Main Authors: LeBel, Catherine, Rosonina, Emanuel, Sealey, David C. F., Pryde, Fiona, Lydall, David, Maringele, Laura, Harrington, Lea A.
Format: Artigo
Sprog:Inglês
Udgivet: Genetics Society of America 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2710150/
https://ncbi.nlm.nih.gov/pubmed/19380905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.109.102939
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