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Distinct dosage requirements for the maintenance of long and short telomeres in mTert heterozygous mice
Telomerase is a ribonucleoprotein containing an essential telomerase RNA template and telomerase reverse transcriptase (TERT) that maintains telomeres. The dosage requirements for mammalian TERT in telomere length homeostasis are not known, but are of importance in cellular senescence, stem cell ren...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2004
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC395926/ https://ncbi.nlm.nih.gov/pubmed/15079066 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401580101 |
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