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Distinct dosage requirements for the maintenance of long and short telomeres in mTert heterozygous mice

Telomerase is a ribonucleoprotein containing an essential telomerase RNA template and telomerase reverse transcriptase (TERT) that maintains telomeres. The dosage requirements for mammalian TERT in telomere length homeostasis are not known, but are of importance in cellular senescence, stem cell ren...

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Autors principals: Erdmann, Natalie, Liu, Yie, Harrington, Lea
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC395926/
https://ncbi.nlm.nih.gov/pubmed/15079066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401580101
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