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Tricyclic Pyrazoles. Part 5. Novel 1,4-Dihydroindeno[1,2-c]pyrazole CB2 Ligands Using Molecular Hybridization Based on Scaffold Hopping

In search of new selective CB2 ligands, the synthesis and preliminary biological evaluation of novel 1,4-dihydroindeno[1,2-c]pyrazole hybrids of the highly potent prototypicals 5-(4-chloro-3-methylphenyl)-1-(4-methylbenzyl)-N-fenchyl-1H-pyrazole-3-carboxamide 1 and 1-(2,4-dichlorophenyl)-6-methyl-N-...

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書誌詳細
主要な著者: Murineddu, Gabriele, Asproni, Battistina, Ruiu, Stefania, Deligia, Francesco, Falzoi, Matteo, Pau, Amedeo, Thomas, Brian F, Zhang, Yanan, Pinna, Gérard A, Pani, Luca, Lazzari, Paolo
フォーマット: Artigo
言語:Inglês
出版事項: Bentham Open 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406267/
https://ncbi.nlm.nih.gov/pubmed/22876271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1874104501206010001
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