Synthesis and Cytotoxicity of Novel Hexahydrothieno-cycloheptapyridazinone Derivatives

Designed as a new group of tricyclic molecules containing the thienocycloheptapyridazinone ring system, a number of 2N-substituted-hexahydrothieno-cycloheptapyridazinone derivatives were synthesized and their biological activity evaluated. Among the synthesized compounds, derivatives 7d and 7h were...

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Published in:Molecules
Main Authors: Pau, Amedeo, Murineddu, Gabriele, Asproni, Battistina, Murruzzu, Caterina, Grella, Giuseppe E., Pinna, Gérard A., Curzu, Maria M., Marchesi, Irene, Bagella, Luigi
Format: Artigo
Language:Inglês
Published: Molecular Diversity Preservation International 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6254715/
https://ncbi.nlm.nih.gov/pubmed/19783939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules14093494
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