Intact p53-Dependent Responses in miR-34–Deficient Mice

MicroRNAs belonging to the miR-34 family have been proposed as critical modulators of the p53 pathway and potential tumor suppressors in human cancers. To formally test these hypotheses, we have generated mice carrying targeted deletion of all three members of this microRNA family. We show that comp...

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Библиографические подробности
Главные авторы: Concepcion, Carla P., Han, Yoon-Chi, Mu, Ping, Bonetti, Ciro, Yao, Evelyn, D'Andrea, Aleco, Vidigal, Joana A., Maughan, William P., Ogrodowski, Paul, Ventura, Andrea
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2012
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406012/
https://ncbi.nlm.nih.gov/pubmed/22844244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002797
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