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An allelic series of miR-17~92 mutant mice uncovers functional specialization and cooperation among members of a miRNA polycistron
Polycistronic microRNA clusters are a common feature of vertebrate genomes. The coordinated expression of miRNAs belonging to different seed families from a single transcription unit suggests functional cooperation, but this hypothesis has not been experimentally tested. Here we report the character...
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| Publicat a: | Nat Genet |
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| Autors principals: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4485521/ https://ncbi.nlm.nih.gov/pubmed/26029871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3321 |
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