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A Drosophila model of Spinal Muscular Atrophy uncouples the snRNP biogenesis functions of survival motor neuron from locomotion and viability defects
The Spinal Muscular Atrophy (SMA) protein, survival motor neuron (SMN), functions in the biogenesis of small nuclear ribonucleoproteins (snRNPs). SMN has also been implicated in tissue-specific functions, however, it remains unclear which of these is important for the etiology of SMA. Smn null mutan...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3405901/ https://ncbi.nlm.nih.gov/pubmed/22813737 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2012.05.014 |
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