Development of an MRI-visible nonviral vector for siRNA delivery targeting gastric cancer

An antibody-directed nonviral vector, polyethylene glycol-grafted polyethylenimine functionalized with superparamagnetic iron oxide nanoparticles and a gastric cancer-associated CD44v6 single-chain variable fragment (scFv(CD44v6),-PEG-g-PEI-SPION), was constructed as a gastric cancer-targeting and m...

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Bibliographic Details
Main Authors: Chen, Yinting, Wang, Weiwei, Lian, Guoda, Qian, Chenchen, Wang, Lingyun, Zeng, Linjuan, Liao, Chengde, Liang, Biling, Huang, Bing, Huang, Kaihong, Shuai, Xintao
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2012
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405872/
https://ncbi.nlm.nih.gov/pubmed/22848158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S24083
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