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An MRI-visible non-viral vector for targeted Bcl-2 siRNA delivery to neuroblastoma
Polyethylene glycol-grafted polyethylenimine (PEG-g-PEI) which was functionalized with a neuroblastoma cell-specific ligand, the GD2 single chain antibody (scAb(GD2)), was synthesized in order to effectively deliver Bcl-2 siRNA into neuroblastoma cells. This polymer was complexed first with superpar...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3396391/ https://ncbi.nlm.nih.gov/pubmed/22802690 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S32900 |
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