LATS1/WARTS phosphorylates MYPT1 to counteract PLK1 and regulate mammalian mitotic progression

In the mitotic exit network of budding yeast, Dbf2 kinase phosphorylates and regulates Cdc14 phosphatase. In contrast, no phosphatase substrates of LATS1/WARTS kinase, the mammalian equivalent of Dbf2, has been reported. To address this discrepancy, we performed phosphoproteomic screening using LATS...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Chiyoda, Tatsuyuki, Sugiyama, Naoyuki, Shimizu, Takatsune, Naoe, Hideaki, Kobayashi, Yusuke, Ishizawa, Jo, Arima, Yoshimi, Tsuda, Hiroshi, Ito, Masaaki, Kaibuchi, Kozo, Aoki, Daisuke, Ishihama, Yasushi, Saya, Hideyuki, Kuninaka, Shinji
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2012
Soggetti:
Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404884/
https://ncbi.nlm.nih.gov/pubmed/22641346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201110110
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi