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The Anaphase-Promoting Complex/Cyclosome Activator Cdh1 Modulates Rho GTPase by Targeting p190 RhoGAP for Degradation

Cdh1 is an activator of the anaphase-promoting complex/cyclosome and contributes to mitotic exit and G(1) maintenance by targeting cell cycle proteins for degradation. However, Cdh1 is expressed and active in postmitotic or quiescent cells, suggesting that it has functions other than cell cycle cont...

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Bibliographische Detailangaben
Hauptverfasser: Naoe, Hideaki, Araki, Kimi, Nagano, Osamu, Kobayashi, Yusuke, Ishizawa, Jo, Chiyoda, Tatsuyuki, Shimizu, Takatsune, Yamamura, Ken-ichi, Sasaki, Yutaka, Saya, Hideyuki, Kuninaka, Shinji
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2010
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916440/
https://ncbi.nlm.nih.gov/pubmed/20530197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01358-09
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