LATS1 and LATS2 Phosphorylate CDC26 to Modulate Assembly of the Tetratricopeptide Repeat Subcomplex of APC/C

In budding yeast, the Mitotic Exit Network (MEN) regulates anaphase promoting complex/cyclosome (APC/C) via the Dbf2-Cdc14 signaling cascade. Dbf2 kinase phosphorylates and activates Cdc14 phosphatase, which removes the inhibitory phosphorylation of the APC/C cofactor Cdh1. Although each component o...

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Udgivet i:PLoS One
Main Authors: Masuda, Kenta, Chiyoda, Tatsuyuki, Sugiyama, Naoyuki, Segura-Cabrera, Aldo, Kabe, Yasuaki, Ueki, Arisa, Banno, Koji, Suematsu, Makoto, Aoki, Daisuke, Ishihama, Yasushi, Saya, Hideyuki, Kuninaka, Shinji
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4344199/
https://ncbi.nlm.nih.gov/pubmed/25723520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118662
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