Establishment of a Choriocarcinoma Model from Immortalized Normal Extravillous Trophoblast Cells Transduced with HRASV12

Gestational choriocarcinoma is a malignant trophoblastic tumor. The development of novel molecular-targeted therapies is needed to reduce the toxicity of current multiagent chemotherapy and to treat successfully the chemoresistant cases. The molecular mechanisms underlying choriocarcinoma tumorigene...

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Detalhes bibliográficos
Main Authors: Kobayashi, Yusuke, Shimizu, Takatsune, Naoe, Hideaki, Ueki, Arisa, Ishizawa, Joe, Chiyoda, Tatsuyuki, Onishi, Nobuyuki, Sugihara, Eiji, Nagano, Osamu, Banno, Kouji, Kuninaka, Shinji, Aoki, Daisuke, Saya, Hideyuki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2011
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157189/
https://ncbi.nlm.nih.gov/pubmed/21787741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.05.019
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