The histone acetyltransferase PCAF regulates p21 transcription through stress-induced acetylation of histone H3

The activity of p53 as a tumor suppressor primarily depends on its ability to transactivate specific target genes in response to genotoxic and other potentially mutagenic stresses. Several histone acetyl transferases (HATs), including p300, CBP, PCAF and GCN5 have been implicated in the activation o...

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Bibliografiske detaljer
Main Authors: Love, Ian M., Sekaric, Pedja, Shi, Dingding, Grossman, Steven R., Androphy, Elliot J.
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2012
Fag:
Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404877/
https://ncbi.nlm.nih.gov/pubmed/22713239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.20864
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