Influenza A virus nucleoprotein is acetylated by histone acetyltransferases PCAF and GCN5

Histone acetylation plays crucial roles in transcriptional regulation and chromatin organization. Viral RNA of the influenza virus interacts with its nucleoprotein (NP), whose function corresponds to that of eukaryotic histones. NP regulates viral replication and has been shown to undergo acetylatio...

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Gepubliceerd in:J Biol Chem
Hoofdauteurs: Hatakeyama, Dai, Shoji, Masaki, Yamayoshi, Seiya, Yoh, Rina, Ohmi, Naho, Takenaka, Shiori, Saitoh, Ayaka, Arakaki, Yumie, Masuda, Aki, Komatsu, Tsugunori, Nagano, Rina, Nakano, Masahiro, Noda, Takeshi, Kawaoka, Yoshihiro, Kuzuhara, Takashi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2018
Onderwerpen:
Microbiology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5950015/
https://ncbi.nlm.nih.gov/pubmed/29555684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001683
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