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Stimulation of DNA Replication from the Polyomavirus Origin by PCAF and GCN5 Acetyltransferases: Acetylation of Large T Antigen

The PCAF and GCN5 acetyltransferases, but not p300 or CBP, stimulate DNA replication when tethered near the polyomavirus origin. Replication stimulation by PCAF and GCN5 is blocked by mutational inactivation of their acetyltransferase domains but not by deletion of sequences that bind p300 or CBP. A...

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Udgivet i:Mol Cell Biol
Principais autores: Xie, An-Yong, Bermudez, Vladimir P., Folk, William R.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2002
Fag:
DNA Dynamics and Chromosome Structure
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC134729/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12391158/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.22.7907-7918.2002
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