Stimulation of DNA Replication from the Polyomavirus Origin by PCAF and GCN5 Acetyltransferases: Acetylation of Large T Antigen

The PCAF and GCN5 acetyltransferases, but not p300 or CBP, stimulate DNA replication when tethered near the polyomavirus origin. Replication stimulation by PCAF and GCN5 is blocked by mutational inactivation of their acetyltransferase domains but not by deletion of sequences that bind p300 or CBP. A...

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Detalhes bibliográficos
Main Authors: Xie, An-Yong, Bermudez, Vladimir P., Folk, William R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
DNA Dynamics and Chromosome Structure
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC134729/
https://ncbi.nlm.nih.gov/pubmed/12391158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.22.7907-7918.2002
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