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The histone acetyltransferase PCAF regulates p21 transcription through stress-induced acetylation of histone H3
The activity of p53 as a tumor suppressor primarily depends on its ability to transactivate specific target genes in response to genotoxic and other potentially mutagenic stresses. Several histone acetyl transferases (HATs), including p300, CBP, PCAF and GCN5 have been implicated in the activation o...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Landes Bioscience
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3404877/ https://ncbi.nlm.nih.gov/pubmed/22713239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.20864 |
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