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Ca(2+) responses of pulmonary arterial myocytes to acute hypoxia require release from ryanodine and inositol trisphosphate receptors in sarcoplasmic reticulum

In pulmonary arterial smooth muscle cells (PASMC), acute hypoxia increases intracellular Ca(2+) concentration ([Ca(2+)](i)) by inducing Ca(2+) release from the sarcoplasmic reticulum (SR) and Ca(2+) influx through store- and voltage-operated Ca(2+) channels in sarcolemma. To evaluate the mechanisms...

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Bibliografiske detaljer
Main Authors: Wang, Jian, Shimoda, Larissa A., Sylvester, J. T.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404627/
https://ncbi.nlm.nih.gov/pubmed/22582116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00348.2011
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