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Obstruction of ventricular Ca(2+)‐dependent arrhythmogenicity by inositol 1,4,5‐trisphosphate‐triggered sarcoplasmic reticulum Ca(2+) release

KEY POINTS: Augmented inositol 1,4,5‐trisphosphate (IP(3)) receptor (IP(3)R2) expression has been linked to a variety of cardiac pathologies. Although cardiac IP(3)R2 function has been in the focus of research for some time, a detailed understanding of its potential role in ventricular myocyte excit...

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Vydáno v:J Physiol
Hlavní autoři: Blanch i Salvador, Joaquim, Egger, Marcel
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6138286/
https://ncbi.nlm.nih.gov/pubmed/30004117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP276319
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