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Intracellular Amyloid Precursor Protein Sorting and Amyloid-β Secretion Are Regulated by Src-Mediated Phosphorylation of Mint2
Mint adaptor proteins bind to the membrane-bound amyloid precursor protein (APP) and affect the production of pathogenic amyloid-β (Aβ) peptides related to Alzheimer's disease (AD). Previous studies have shown that loss of each of the three Mint proteins delays the age-dependent production of a...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3404619/ https://ncbi.nlm.nih.gov/pubmed/22787047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0602-12.2012 |
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