Targeting the CXCR4-CXCL12 axis mobilizes autologous hematopoietic stem cells and prolongs islet allograft survival via PD-L1

Antagonism of CXCR4 disrupts the interaction between the CXCR4 receptor on HSCs and the CXCL12 expressed by stromal cells in the bone marrow, which subsequently results in the shedding of hematopoietic stem cells (HSCs) to the periphery. Due to their profound immunomodulatory effects, HSCs have emer...

詳細記述

保存先:
書誌詳細
主要な著者: Fiorina, Paolo, Jurewicz, Mollie, Vergani, Andrea, Petrelli, Alessandra, Carvello, Michele, D’Addio, Francesca, Godwin, Jonathan G., Law, Kenneth, Wu, Erxi, Tian, Ze, Thoma, Gebhard, Kovarik, Jiri, La Rosa, Stefano, Capella, Carlo, Rodig, Scott, Zerwes, Hans-Guenter, Sayegh, Mohamed H., Abdi, Reza
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404615/
https://ncbi.nlm.nih.gov/pubmed/21131428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000799
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料