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ATP mediates flow-induced NO production in thick ascending limbs

Mechanical stimulation caused by increasing flow induces nucleotide release from many cells. Luminal flow and extracellular ATP stimulate production of nitric oxide (NO) in thick ascending limbs. However, the factors that mediate flow-induced NO production are unknown. We hypothesized that luminal f...

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Autors principals: Cabral, Pablo D., Hong, Nancy J., Garvin, Jeffrey L.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404590/
https://ncbi.nlm.nih.gov/pubmed/22496412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00504.2011
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