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Cystic fibrosis transmembrane conductance regulator contributes to reacidification of alkalinized lysosomes in RPE cells

The role of the cystic fibrosis transmembrane conductance regulator (CFTR) in lysosomal acidification has been difficult to determine. We demonstrate here that CFTR contributes more to the reacidification of lysosomes from an elevated pH than to baseline pH maintenance. Lysosomal alkalinization is i...

詳細記述

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書誌詳細
主要な著者: Liu, Ji, Lu, Wennan, Guha, Sonia, Baltazar, Gabriel C., Coffey, Erin E., Laties, Alan M., Rubenstein, Ronald C., Reenstra, William W., Mitchell, Claire H.
フォーマット: Artigo
言語:Inglês
出版事項: American Physiological Society 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404519/
https://ncbi.nlm.nih.gov/pubmed/22572847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00278.2011
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