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Copper-Catalyzed Azide–Alkyne Click Chemistry for Bioconjugation
The copper-catalyzed azide-alkyne cycloaddition reaction is widely used for the connection of molecular entities of all sizes. A protocol is provided here for the process with biomolecules. Ascorbate is used as reducing agent to maintain the required cuprous oxidation state. Since these convenient c...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3404492/ https://ncbi.nlm.nih.gov/pubmed/22844652 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/9780470559277.ch110148 |
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