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Decreased Levels of Secretory Leucoprotease Inhibitor in the Pseudomonas-infected Cystic Fibrosis Lung are due to Neutrophil Elastase Degradation()

Secretory leucoprotease inhibitor (SLPI) is a neutrophil serine protease inhibitor constitutively expressed at many mucosal surfaces including that of the lung. Originally identified as a serine protease inhibitor, it is now evident that SLPI also has anti-microbial and anti-inflammatory functions,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Weldon, Sinéad, McNally, Paul, McElvaney, Noel G., Elborn, J. Stuart, McAuley, Danny F., Wartelle, Julien, Belaaouaj, Abderrazzaq, Levine, Rodney L., Taggart, Clifford C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404409/
https://ncbi.nlm.nih.gov/pubmed/20007580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901716
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