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Control of viral latency in neurons by axonal mTOR signaling and the 4E-BP translation repressor
Latent herpes simplex virus-1 (HSV1) genomes in peripheral nerve ganglia periodically reactivate, initiating a gene expression program required for productive replication. Whether molecular cues detected by axons can be relayed to cell bodies and harnessed to regulate latent genome expression in neu...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3404381/ https://ncbi.nlm.nih.gov/pubmed/22802527 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.190157.112 |
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