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shutdown is a component of the Drosophila piRNA biogenesis machinery
In animals, the piRNA pathway preserves the integrity of gametic genomes, guarding them against the activity of mobile genetic elements. This innate immune mechanism relies on distinct genomic loci, termed piRNA clusters, to provide a molecular definition of transposons, enabling their discriminatio...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3404366/ https://ncbi.nlm.nih.gov/pubmed/22753781 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.034405.112 |
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