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The piRNA pathway in flies: highlights and future directions

Piwi proteins, together with their bound Piwi-interacting RNAs, constitute an evolutionarily conserved, germline-specific innate immune system. The piRNA pathway is one of the key mechanisms for silencing transposable elements in the germline, thereby preserving genome integrity between generations....

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Autors principals: Guzzardo, Paloma M, Muerdter, Felix, Hannon, Gregory J
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3621807/
https://ncbi.nlm.nih.gov/pubmed/23317515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2012.12.003
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