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shutdown is a component of the Drosophila piRNA biogenesis machinery

In animals, the piRNA pathway preserves the integrity of gametic genomes, guarding them against the activity of mobile genetic elements. This innate immune mechanism relies on distinct genomic loci, termed piRNA clusters, to provide a molecular definition of transposons, enabling their discriminatio...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Preall, Jonathan B., Czech, Benjamin, Guzzardo, Paloma M., Muerdter, Felix, Hannon, Gregory J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404366/
https://ncbi.nlm.nih.gov/pubmed/22753781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.034405.112
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