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Identification of a Novel Actin-Binding Domain within the Rho Guanine Nucleotide Exchange Factor TEM4

Spatio-temporal activation of Rho GTPases is essential for their function in a variety of biological processes and is achieved in part by regulating the localization of their activators, the Rho guanine nucleotide exchange factors (RhoGEFs). In this study, we provide the first characterization of th...

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Detalhes bibliográficos
Main Authors: Mitin, Natalia, Rossman, Kent L., Der, Channing J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404065/
https://ncbi.nlm.nih.gov/pubmed/22911862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041876
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