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The RhoGEF TEM4 Regulates Endothelial Cell Migration by Suppressing Actomyosin Contractility

Persistent cellular migration requires efficient protrusion of the front of the cell, the leading edge where the actin cytoskeleton and cell-substrate adhesions undergo constant rearrangement. Rho family GTPases are essential regulators of the actin cytoskeleton and cell adhesion dynamics. Here, we...

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Detalhes bibliográficos
Main Authors: Mitin, Natalia, Rossman, Kent L., Currin, Rachel, Anne, Sandeep, Marshall, Thomas W., Bear, James E., Bautch, Victoria L., Der, Channing J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3688894/
https://ncbi.nlm.nih.gov/pubmed/23825001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066260
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