The RhoGEF TEM4 Regulates Endothelial Cell Migration by Suppressing Actomyosin Contractility

Persistent cellular migration requires efficient protrusion of the front of the cell, the leading edge where the actin cytoskeleton and cell-substrate adhesions undergo constant rearrangement. Rho family GTPases are essential regulators of the actin cytoskeleton and cell adhesion dynamics. Here, we...

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Bibliographic Details
Main Authors: Mitin, Natalia, Rossman, Kent L., Currin, Rachel, Anne, Sandeep, Marshall, Thomas W., Bear, James E., Bautch, Victoria L., Der, Channing J.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3688894/
https://ncbi.nlm.nih.gov/pubmed/23825001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066260
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