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Fra-1/AP-1 Transcription Factor Negatively Regulates Pulmonary Fibrosis In Vivo

The Fra-1/AP-1 transcription factor plays a key role in tumor epithelial cell progression; however, its role in pathogenic lung fibrosis remains unclear. In the present study, using a genetic approach (Fra-1 deficient mice), we have demonstrated a novel regulatory (protective) role for Fra-1 in lung...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Rajasekaran, Subbiah, Vaz, Michelle, Reddy, Sekhar P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404039/
https://ncbi.nlm.nih.gov/pubmed/22911824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041611
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