Development of pulmonary fibrosis through a pathway involving the transcription factor Fra-2/AP-1

Studies using genetically modified mice have revealed fundamental functions of the transcription factor Fos/AP-1 in bone biology, inflammation, and cancer. However, the biological role of the Fos-related protein Fra-2 is not well defined in vivo. Here we report an unexpected profibrogenic function o...

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Bibliografiska uppgifter
Huvudupphovsmän: Eferl, Robert, Hasselblatt, Peter, Rath, Martina, Popper, Helmut, Zenz, Rainer, Komnenovic, Vukoslav, Idarraga, Maria-Helena, Kenner, Lukas, Wagner, Erwin F.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2008
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2492511/
https://ncbi.nlm.nih.gov/pubmed/18641127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0801414105
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