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The Fos-related antigen Fra-1 is an activator of bone matrix formation
Ectopic expression of the transcription factor Fra-1 in transgenic mice leads to osteosclerosis, a bone disorder characterized by increased bone mass. The molecular basis for this phenotype is unknown and Fra-1 functions cannot be studied by a conventional loss-of-function approach, since fra-1-knoc...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2004
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC514946/ https://ncbi.nlm.nih.gov/pubmed/15229648 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600282 |
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