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Mice lacking JunB are osteopenic due to cell-autonomous osteoblast and osteoclast defects
Because JunB is an essential gene for placentation, it was conditionally deleted in the embryo proper. JunB (Δ/Δ) mice are born viable, but develop severe low turnover osteopenia caused by apparent cell-autonomous osteoblast and osteoclast defects before a chronic myeloid leukemia-like disease. Alth...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2171977/ https://ncbi.nlm.nih.gov/pubmed/14769860 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200308155 |
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