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Th2 cell-specific cytokine expression and allergen-induced airway inflammation depend on JunB
Naïve CD4+ T cells differentiate into effector T helper 1 (Th1) or Th2 cells, which are classified by their specific set of cytokines. Here we demonstrate that loss of JunB in in vitro polarized Th2 cells led to a dysregulated expression of the Th2-specific cytokines IL-4 and IL-5. These cells produ...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC136952/ https://ncbi.nlm.nih.gov/pubmed/12456639 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf648 |
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