Th2 cell-specific cytokine expression and allergen-induced airway inflammation depend on JunB

Naïve CD4+ T cells differentiate into effector T helper 1 (Th1) or Th2 cells, which are classified by their specific set of cytokines. Here we demonstrate that loss of JunB in in vitro polarized Th2 cells led to a dysregulated expression of the Th2-specific cytokines IL-4 and IL-5. These cells produ...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Hartenstein, Bettina, Teurich, Sibylle, Hess, Jochen, Schenkel, Johannes, Schorpp-Kistner, Marina, Angel, Peter
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 2002
Assuntos:	Articles
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136952/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12456639/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf648
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