Th2 cell-specific cytokine expression and allergen-induced airway inflammation depend on JunB
Naïve CD4+ T cells differentiate into effector T helper 1 (Th1) or Th2 cells, which are classified by their specific set of cytokines. Here we demonstrate that loss of JunB in in vitro polarized Th2 cells led to a dysregulated expression of the Th2-specific cytokines IL-4 and IL-5. These cells produ...
Kaydedildi:
| Yayımlandı: | EMBO J |
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| Asıl Yazarlar: | , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group
2002
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136952/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12456639/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf648 |
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