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Genetic Disruption of Fra-1 Decreases Susceptibility to Endotoxin-Induced Acute Lung Injury and Mortality in Mice

The activator protein–1 (AP-1) transcription factor, comprising Jun and Fos family proteins, distinctly regulates various cellular processes, including those involved in inflammation. FOS like antigen 1 (Fra-1), a member of the Fos family, dimerizes with members of the Jun family and regulates gene...

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Bibliografiske detaljer
Main Authors: Vaz, Michelle, Reddy, Narsa M., Rajasekaran, Subbiah, Reddy, Sekhar P.
Format: Artigo
Sprog:Inglês
Udgivet: American Thoracic Society 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262652/
https://ncbi.nlm.nih.gov/pubmed/21816965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2011-0169OC
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