Nef functions in BLT mice to enhance HIV-1 replication and deplete CD4(+)CD8(+) thymocytes

BACKGROUND: The outcome of untreated HIV-1 infection is progression to AIDS and death in nearly all cases. Some important exceptions are the small number of patients infected with HIV-1 deleted for the accessory gene, nef. With these infections, disease progression is entirely suppressed or greatly...

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Dettagli Bibliografici
Autori principali: Zou, Wei, Denton, Paul W, Watkins, Richard L, Krisko, John F, Nochi, Tomonori, Foster, John L, Garcia, J Victor
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3403983/
https://ncbi.nlm.nih.gov/pubmed/22640559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-9-44
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